Transforming the care of hypertrophic cardiomyopathy and related conditions.

We seek to deliver better outcomes and quality of life for patients.

Our Science

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Our Approach

Our Approach

Our Approach

Overactive myosin plays a key role in hypertrophic cardiomyopathy. Our approach is to selectively address this underlying mechanism to improve heart performance.

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About HCM

About HCM

About HCM

Hypertrophic cardiomyopathy (HCM) is among the most common rare diseases, affecting approximately 1 in 500 individuals in the United States.

In HCM, the heart contracts with excessive force, causing the heart muscle to become abnormally thick, particularly in the left ventricle—the heart's main pumping chamber.

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Pipeline

Pipeline

Pipeline

We are advancing our investigational treatment through global late-stage clinical development.

Interested in joining our team?

Learn more about our openings.